#mutation #genetics #statistical-model


Utility functions for determining potential point mutations in a genetic sequence and their statisical probability

5 releases

0.2.7 Oct 3, 2021
0.2.5 Feb 17, 2021
0.2.4 Feb 5, 2021
0.2.3 Dec 15, 2020
0.2.0 Aug 5, 2020

#573 in Rust patterns

27 downloads per month
Used in genovo

MIT and LGPL-3.0

1.5K SLoC

Utility library for determining the probability of point mutations

This library is faily specific for my own purposes. It's on crates.io so that I can pull it as a dependency for my project. The code is mature at this point. But it could really use some more doc comments.

This library reads genomic sequences of transcripts and mutates every nucleotide in that transcript to determine how many mutations of a type (synonymous, missense, nonsense, ...) can be generated and what their probabilities are. This is useful to when you try to identify disease genes by comparing mutated genes across affected individuals and you need to determine how many mutations you can expect by chance.


~23K SLoC