#crispr #sequencing #bioinformatics #sg-rna

intc

An implementation of the *-INC method to calculate an empirical FDR for non-targeting controls in CRISPR screens

10 releases

0.3.3 May 22, 2023
0.3.2 May 22, 2023
0.2.1 May 17, 2023
0.1.4 Feb 2, 2023

#4 in #crispr

49 downloads per month
Used in crispr_screen

MIT license

45KB
1K SLoC

intc

Including Non-Targeting Controls

This is a library to perform mann-whitney U tests to aggregate sgRNA enrichment p-values at the gene-level and calculate an empirical false discovery rate via bootstrapping of pseudo-genes composed of non-targeting controls.

Dependencies

~9MB
~165K SLoC