solana-signature is used at run time in 94 crates (of which 12 optionally). It is a direct run-time dependency in 6 crates. It's used only as a dev dependency in 19 crates.

Depender (with downloads and own rev deps) solana-signature version
166K 618 solana-sdk optional =2.1.1
13K 3 solana-transaction-status-client-types =2.1.1
240 2 solana-keypair ^2.1.0
120 2 solana-signer ^2.1.0
110 solana-presigner ^2.1.0
110 solana-transaction-context optional ^2.1.0